emotional abuse SPECIALE SOPSI 2013 - Joachim Klosterkotter: the prediction and prevention of schizophrenia

J. Klosterkotter - Department of Psychiatry and Psychotherapy, University of
Cologne
Recent focus on early detection and intervention in psychosis has renewed interest in subtle psychopathology beyond positive and negative symptoms. Such self-experienced sub-clinicaldisturbances are described in detail by the basic symptom concept.
This review will give an introduction into the concept of basic symptoms and describe the development of the current instruments for their assessment, the Schizophrenia Proneness
Instrument, Adult (SPI-A) and Child and Youth version (SPI-CY), as well as of the two at-risk criteria: the at-risk criterion Cognitive-Perceptive Basic Symptoms (COPER) and the high-risk criterion Cognitive Disturbances (COGDIS).
Further, an overview of prospective studies using both or either basic symptom criteria and transition rates related to these will be given, and the potential benefit of combining ultra-high risk criteria, particularly attenuated psychotic symptoms, and basic symptom criteria will be discussed.
Finally, their prevalence in psychosis patients, i.e. the sensitivity, as well as in general
population samples will be described.
It is concluded that both COPER and COGDIS are able to identify subjects at a high risk of developing psychosis. Further, they appear to be sufficiently frequent prior to onset of the first psychotic episode as well as sufficiently rare in persons of general population to be considered as valuable for an early detection of psychosis.

emotional abuse SPECIALE SOPSI 2013 - Joachim Klosterkotter: the prediction and prevention of schizophrenia
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Science & Technology	Upload TimePublished on 20 Feb 2013

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